Marsden State High School has a diverse curriculum that caters for the needs and interests of a diverse student population.

Curriculum areas include English, Creative and Performing Arts, Mathematics, Sciences, Information Technology, Health and Physical Education, Study of Society & Environment (SOSE), Languages Other Than English (LOTE), Business Education and Industrial Technology.

Marsden State High School has as strong focus on Middle Schooling, Senior Schooling, Vocational Education and Distance Education.